Efficient, divergent synthesis of cryptophycin unit A analogues.
نویسندگان
چکیده
A flexible and divergent synthesis of cryptophycin unit A analogues is described. This method relies on iridium-catalysed stereo- and enantioselective crotylation and chemoselective one-pot oxidative olefination to access common intermediate . Heck, cross metathesis, and Suzuki-Miyaura reactions are illustrated for the generation of methyl ester unit A analogues .
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ورودعنوان ژورنال:
- Chemical communications
دوره شماره
صفحات -
تاریخ انتشار 2012